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Free fatty acid receptor 3
Symbols FFAR3; FFA3R; GPR41
External IDs OMIM603821 MGI2685324 HomoloGene82482 IUPHAR: FFA3 GeneCards: FFAR3 Gene
Species Human Mouse
Entrez 2865 233080
Ensembl n/a ENSMUSG00000019429
UniProt O14843 Q08AU6
RefSeq (mRNA) NM_005304 NM_001033316
RefSeq (protein) NP_005295 NP_001028488
Location (UCSC) n/a Chr 7:
30.56 - 30.56 Mb
PubMed search [1] [2]

Free fatty acid receptor 3 (FFA3) is a G-protein coupled receptor encoded by the FFAR3 gene.[1]


See also


External links

Further reading

  • Brown AJ, Jupe S, Briscoe CP (2005). "A family of fatty acid binding receptors.". DNA Cell Biol. 24 (1): 54–61. doi:10.1089/dna.2005.24.54. PMID 15684720.  
  • Sawzdargo M, George SR, Nguyen T, et al. (1997). "A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.". Biochem. Biophys. Res. Commun. 239 (2): 543–7. doi:10.1006/bbrc.1997.7513. PMID 9344866.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Brown AJ, Goldsworthy SM, Barnes AA, et al. (2003). "The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.". J. Biol. Chem. 278 (13): 11312–9. doi:10.1074/jbc.M211609200. PMID 12496283.  
  • Le Poul E, Loison C, Struyf S, et al. (2003). "Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.". J. Biol. Chem. 278 (28): 25481–9. doi:10.1074/jbc.M301403200. PMID 12711604.  
  • Xiong Y, Miyamoto N, Shibata K, et al. (2004). "Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.". Proc. Natl. Acad. Sci. U.S.A. 101 (4): 1045–50. doi:10.1073/pnas.2637002100. PMID 14722361.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Yonezawa T, Kobayashi Y, Obara Y (2007). "Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.". Cell. Signal. 19 (1): 185–93. doi:10.1016/j.cellsig.2006.06.004. PMID 16887331.  


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