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Fusafungine: Wikis

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Fusafungine
Systematic (IUPAC) name
 ?
Identifiers
CAS number 1393-87-9
ATC code R02AB03
PubChem  ?
Chemical data
Formula C 29H51N2O8  
Mol. mass 555.72 g/mol[1]
Synonyms Fusafungin
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Fusafungine (INN), also known as fusafungin, is an active agent used in antibiotics for treatment of nasal and throat infection. It also possesses anti-inflammatory properties. Fusafungine is a mixture of enniatin cyclohexadepsipeptides made up of alternating D-α-hydroxyvaleric acid and L-N-methylamino acid residues,[2] produced by the ascomycete Fusarium lateritium, and marketed by Servier under the trade names Locabiotal, Bioparox, and Locabiosol.

References

  1. ^ Fusafungine at MeSH
  2. ^ Daniel Levy, Aline Bluzat, Michel Seigneuret and Jean-Louis Rigaud (1995). "Alkali cation transport through liposomes by the antimicrobial fusafungine and its constitutive enniatins". Biochemical Pharmacology 50 (12 22): 2105–2107. doi:10.1016/0006-2952(95)02045-4.  
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