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More info on GBLD-345

GBLD-345: Wikis

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GBLD-345
Systematic (IUPAC) name
2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
Identifiers
CAS number  ?
ATC code  ?
PubChem 4602899
Chemical data
Formula C 21H21N5O2  
Mol. mass 375.423 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a nonselective full agonist at GABAA receptors. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]

References

  1. ^ Davies LP, Barlin GB, Ireland SJ, Ngu MM (October 1992). "Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors". Biochemical Pharmacology 44 (8): 1555–61. PMID 1358075.  
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