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G protein-coupled receptor 125
Symbols GPR125; PGR21; TEM5L
External IDs MGI1917943 HomoloGene19235 IUPHAR: GPR125 GeneCards: GPR125 Gene
RNA expression pattern
PBB GE GPR125 210473 s at tn.png
More reference expression data
Species Human Mouse
Entrez 166647 70693
Ensembl ENSG00000152990 ENSMUSG00000029090
UniProt Q8IWK6 Q3V2C4
RefSeq (mRNA) XM_001131071 XM_132089
RefSeq (protein) XP_001131071 XP_132089
Location (UCSC) Chr 4:
22 - 22.13 Mb
Chr 5:
50.25 - 50.35 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 125 is a protein that in humans is encoded by the GPR125 gene.[1][2]


  1. ^ Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). "There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini". Biochem Biophys Res Commun 301 (3): 725-34. PMID 12565841.  
  2. ^ "Entrez Gene: GPR125 G protein-coupled receptor 125".  

Further reading

  • Seandel M, et al. (2007). "Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.". Nature 449 (7160): 346–50. doi:10.1038/nature06129. PMID 17882221.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Yamamoto Y, Irie K, Asada M, et al. (2004). "Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.". Oncogene 23 (22): 3889–97. doi:10.1038/sj.onc.1207495. PMID 15021905.  
  • Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.". Genomics 84 (1): 23–33. doi:10.1016/j.ygeno.2003.12.004. PMID 15203201.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.  


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