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G protein-coupled receptor 156
Identifiers
Symbols GPR156; GABABL; MGC142261; PGR28
External IDs OMIM610464 MGI2653880 HomoloGene17683 IUPHAR: GPR156 GeneCards: GPR156 Gene
RNA expression pattern
PBB GE GPR156 gnf1h10156 at tn.png
PBB GE GPR156 gnf1h10157 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 165829 239845
Ensembl ENSG00000175697 ENSMUSG00000046961
UniProt Q8NFN8 Q6PCP7
RefSeq (mRNA) NM_153002 NM_153394
RefSeq (protein) NP_694547 NP_700443
Location (UCSC) Chr 3:
121.36 - 121.45 Mb
Chr 16:
37.84 - 37.93 Mb
PubMed search [1] [2]

GPR156 (G protein-coupled receptor 156), is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily.[1] By sequence homology, this gene was proposed as being a possible GABAB receptor subunit, however when expressed in cells alone or with other GABAB subunits, no response to GABAB ligands could be detected. Therefore the function of this protein remains to be elucidated.[2]

References

  1. ^ "Entrez Gene: GPR156 G protein-coupled receptor 156". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=165829.  
  2. ^ Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN (2003). "Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor". Brain Res. Mol. Brain Res. 110 (2): 305–17. doi:10.1016/S0169-328X(02)00662-9. PMID 12591167.  

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Calver AR, Michalovich D, Testa TT, et al. (2003). "Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor.". Brain Res. Mol. Brain Res. 110 (2): 305–17. doi:10.1016/S0169-328X(02)00662-9. PMID 12591167.  
  • Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). "The G protein-coupled receptor repertoires of human and mouse.". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. doi:10.1073/pnas.0230374100. PMID 12679517.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
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