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G protein-coupled receptor 17
Symbols GPR17; DKFZp686M18273
External IDs OMIM603071 MGI3584514 HomoloGene83191 IUPHAR: GPR17 GeneCards: GPR17 Gene
RNA expression pattern
PBB GE GPR17 206190 at tn.png
PBB GE GPR17 215225 s at tn.png
More reference expression data
Species Human Mouse
Entrez 2840 574402
Ensembl ENSG00000144230 ENSMUSG00000052229
UniProt Q13304 n/a
RefSeq (mRNA) NM_005291 NM_001025381
RefSeq (protein) NP_005282 NP_001020552
Location (UCSC) Chr 2:
128.12 - 128.13 Mb
Chr 18:
32.09 - 32.09 Mb
PubMed search [1] [2]

Uracil nucleotide/cysteinyl leukotriene receptor is a protein that in humans is encoded by the GPR17 gene.[1][2]


  1. ^ Raport CJ, Schweickart VL, Chantry D, Eddy RL Jr, Shows TB, Godiska R, Gray PW (Feb 1996). "New members of the chemokine receptor gene family". J Leukoc Biol 59 (1): 18-23. PMID 8558062.  
  2. ^ "Entrez Gene: GPR17 G protein-coupled receptor 17".  

Further reading

  • Macrez-Leprêtre N, Kalkbrenner F, Morel JL, et al. (1997). "G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes.". J. Biol. Chem. 272 (15): 10095–102. doi:10.1074/jbc.272.15.10095. PMID 9092554.  
  • Bläsius R, Weber RG, Lichter P, Ogilvie A (1998). "A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21.". J. Neurochem. 70 (4): 1357–65. PMID 9523551.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  
  • Ciana P, Fumagalli M, Trincavelli ML, et al. (2006). "The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.". EMBO J. 25 (19): 4615–27. doi:10.1038/sj.emboj.7601341. PMID 16990797.  
  • M. Kandhavelu, M. P. Abbracchio, P. Angeli, M. Buccioni, D. Dal Ben, C. Lammi, D. Lecca, G. Marucci, G. Cristalli. “Site directed mutagenesis of GPR17 receptor” 16th Camerino-Noordwijkerhout Symposium “An Overview on Receptor Chemistry, Camerino, September 9-13,P28, 2007.


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