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G protein-coupled receptor 22
Symbols GPR22; MGC129847
External IDs OMIM601910 MGI1920260 HomoloGene18420 IUPHAR: GPR22 GeneCards: GPR22 Gene
RNA expression pattern
PBB GE GPR22 221288 at tn.png
More reference expression data
Species Human Mouse
Entrez 2845 73010
Ensembl ENSG00000172209 ENSMUSG00000044067
UniProt Q99680 n/a
RefSeq (mRNA) NM_005295 NM_175191
RefSeq (protein) NP_005286 NP_780400
Location (UCSC) Chr 7:
106.9 - 106.9 Mb
Chr 12:
32.29 - 32.3 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 22 is a protein that in humans is encoded by the GPR22 gene.[1][2]

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein.[2]


  1. ^ O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF Jr, Lynch KR, George SR (Apr 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene 187 (1): 75-81. PMID 9073069.  
  2. ^ a b "Entrez Gene: GPR22 G protein-coupled receptor 22".  

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.  
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Lee J, Hever A, Willhite D, et al. (2006). "Effects of RNA degradation on gene expression analysis of human postmortem tissues.". Faseb J. 19 (10): 1356–8. doi:10.1096/fj.04-3552fje. PMID 15955843.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  


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