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G protein-coupled receptor 65
Symbols GPR65; TDAG8; hTDAG8
External IDs OMIM604620 MGI108031 HomoloGene2675 IUPHAR: GPR65 GeneCards: GPR65 Gene
RNA expression pattern
PBB GE GPR65 214467 at tn.png
More reference expression data
Species Human Mouse
Entrez 8477 14744
Ensembl ENSG00000140030 ENSMUSG00000021886
UniProt Q8IYL9 Q3UQ35
RefSeq (mRNA) NM_003608 NM_008152
RefSeq (protein) NP_003599 NP_032178
Location (UCSC) Chr 14:
87.54 - 87.55 Mb
Chr 12:
98.67 - 98.68 Mb
PubMed search [1] [2]

Psychosine receptor is a protein that in humans is encoded by the GPR65 gene.[1][2]

See also


  1. ^ Kyaw H, Zeng Z, Su K, Fan P, Shell BK, Carter KC, Li Y (Jul 1998). "Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene". DNA Cell Biol 17 (6): 493-500. PMID 9655242.  
  2. ^ "Entrez Gene: GPR65 G protein-coupled receptor 65".  

Further reading

  • Im DS, Heise CE, Nguyen T, et al. (2001). "Identification of a molecular target of psychosine and its role in globoid cell formation.". J. Cell Biol. 153 (2): 429–34. doi:10.1083/jcb.153.2.429. PMID 11309421.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.  
  • Sin WC, Zhang Y, Zhong W, et al. (2004). "G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers.". Oncogene 23 (37): 6299–303. doi:10.1038/sj.onc.1207838. PMID 15221007.  
  • Wang JQ, Kon J, Mogi C, et al. (2004). "TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor.". J. Biol. Chem. 279 (44): 45626–33. doi:10.1074/jbc.M406966200. PMID 15326175.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Ishii S, Kihara Y, Shimizu T (2005). "Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor.". J. Biol. Chem. 280 (10): 9083–7. doi:10.1074/jbc.M407832200. PMID 15618224.  
  • Radu CG, Nijagal A, McLaughlin J, et al. (2005). "Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells.". Proc. Natl. Acad. Sci. U.S.A. 102 (5): 1632–7. doi:10.1073/pnas.0409415102. PMID 15665078.  


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