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G protein-coupled receptor 75
Symbols GPR75; GPR-chr2; WI-31133
External IDs OMIM606704 MGI2441843 HomoloGene4945 IUPHAR: GPR75 GeneCards: GPR75 Gene
RNA expression pattern
PBB GE GPR75 220481 at tn.png
More reference expression data
Species Human Mouse
Entrez 10936 237716
Ensembl ENSG00000119737 ENSMUSG00000043999
UniProt O95800 Q059L0
RefSeq (mRNA) NM_006794 NM_175490
RefSeq (protein) NP_006785 NP_780699
Location (UCSC) Chr 2:
53.93 - 53.94 Mb
Chr 11:
30.79 - 30.79 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene.[1][2]

GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM][2]


  1. ^ Tarttelin EE, Kirschner LS, Bellingham J, Baffi J, Taymans SE, Gregory-Evans K, Csaky K, Stratakis CA, Gregory-Evans CY (Jul 1999). "Cloning and characterization of a novel orphan G-protein-coupled receptor localized to human chromosome 2p16". Biochem Biophys Res Commun 260 (1): 174-80. doi:10.1006/bbrc.1999.0753. PMID 10381362.  
  2. ^ a b "Entrez Gene: GPR75 G protein-coupled receptor 75".  

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.  


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