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G protein-coupled receptor 78
Symbols GPR78;
External IDs OMIM606921 HomoloGene50960 IUPHAR: GPR78 GeneCards: GPR78 Gene
Species Human Mouse
Entrez 27201 n/a
Ensembl ENSG00000155269 n/a
UniProt Q96P69 n/a
RefSeq (mRNA) NM_080819 n/a
RefSeq (protein) NP_543009 n/a
Location (UCSC) Chr 4:
8.63 - 8.64 Mb
PubMed search [1] n/a

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.[1][2]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM][2]


  1. ^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene 275 (1): 83-91. PMID 11574155.  
  2. ^ a b "Entrez Gene: GPR78 G protein-coupled receptor 78".  

Further reading

  • van Laar T, Schouten T, Hoogervorst E, et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway.". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Underwood SL, Christoforou A, Thomson PA, et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.". Mol. Psychiatry 11 (4): 384–94. doi:10.1038/ PMID 16389273.  


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