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G protein-coupled receptor 85
Symbols GPR85; SREB; SREB2
External IDs OMIM605188 MGI1927851 HomoloGene10355 IUPHAR: GPR85 GeneCards: GPR85 Gene
RNA expression pattern
PBB GE GPR85 219898 at tn.png
More reference expression data
Species Human Mouse
Entrez 54329 64450
Ensembl ENSG00000164604 ENSMUSG00000048216
UniProt P60893 Q6ZWR2
RefSeq (mRNA) NM_018970 NM_145066
RefSeq (protein) NP_061843 NP_659503
Location (UCSC) Chr 7:
112.51 - 112.52 Mb
Chr 6:
13.79 - 13.79 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene.[1][2][3]

See also


  1. ^ Hellebrand S, Schaller HC, Wittenberger T (Nov 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochim Biophys Acta 1493 (1-2): 269-72. PMID 10978537.  
  2. ^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun 272 (2): 576-82. doi:10.1006/bbrc.2000.2829. PMID 10833454.  
  3. ^ "Entrez Gene: GPR85 G protein-coupled receptor 85".  

Further reading

  • "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. PMID 9847074.  
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMID 11076863.  
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.  
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.  
  • Jeon J, Kim C, Sun W, et al. (2002). "Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor.". Biochem. Biophys. Res. Commun. 298 (4): 613–8. doi:10.1016/S0006-291X(02)02515-9. PMID 12408996.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.  
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.  
  • Matsumoto M, Beltaifa S, Weickert CS, et al. (2005). "A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain.". Brain Res. Mol. Brain Res. 138 (1): 58–69. doi:10.1016/j.molbrainres.2005.04.002. PMID 15893849.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.  


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