The Full Wiki

More info on GPRC5B

GPRC5B: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
G protein-coupled receptor, family C, group 5, member B
Identifiers
Symbols GPRC5B; RAIG-2; RAIG2
External IDs OMIM605948 MGI1927596 HomoloGene9435 IUPHAR: RAIG2 GeneCards: GPRC5B Gene
RNA expression pattern
PBB GE GPRC5B 203632 s at tn.png
PBB GE GPRC5B 203631 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 51704 64297
Ensembl ENSG00000167191 ENSMUSG00000008734
UniProt Q9NZH0 Q9JMF0
RefSeq (mRNA) NM_016235 NM_022420
RefSeq (protein) NP_057319 NP_071865
Location (UCSC) Chr 16:
19.78 - 19.8 Mb
Chr 7:
118.76 - 118.79 Mb
PubMed search [1] [2]

G-protein coupled receptor family C group 5 member B is a protein that in humans is encoded by the GPRC5B gene.[1][2][3]

The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade.[3]

Contents

See also

References

  1. ^ Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics 60 (3): 295-308. doi:10.1006/geno.1999.5927. PMID 10493829.  
  2. ^ Brauner-Osborne H, Krogsgaard-Larsen P (Jul 2000). "Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain". Genomics 65 (2): 121-8. doi:10.1006/geno.2000.6164. PMID 10783259.  
  3. ^ a b "Entrez Gene: GPRC5B G protein-coupled receptor, family C, group 5, member B". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51704.  

External links

Further reading

  • Robbins MJ, Michalovich D, Hill J, et al. (2001). "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).". Genomics 67 (1): 8–18. doi:10.1006/geno.2000.6226. PMID 10945465.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message