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GTF3A: Wikis


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From Wikipedia, the free encyclopedia

General transcription factor IIIA
Symbols GTF3A; AP2; TFIIIA
External IDs OMIM600860 GeneCards: GTF3A Gene
Species Human Mouse
Entrez 2971 n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) NM_002097 n/a
RefSeq (protein) NP_002088 n/a
Location (UCSC) n/a n/a
PubMed search [1] n/a

Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.[1][2]


  1. ^ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenet Cell Genet 70 (3-4): 235-8. PMID 7789179.  
  2. ^ "Entrez Gene: GTF3A general transcription factor IIIA".  

Further reading

  • Murphy JE, Keen JH (1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia.". J. Biol. Chem. 267 (15): 10850–5. PMID 1587861.  
  • Seifart KH, Wang L, Waldschmidt R, et al. (1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA.". J. Biol. Chem. 264 (3): 1702–9. PMID 2912980.  
  • Drew PD, Nagle JW, Canning RD, et al. (1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA.". Gene 159 (2): 215–8. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.  
  • Moorefield B, Roeder RG (1994). "Purification and characterization of human transcription factor IIIA.". J. Biol. Chem. 269 (33): 20857–65. PMID 8063702.  
  • Fridell RA, Fischer U, Lührmann R, et al. (1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev.". Proc. Natl. Acad. Sci. U.S.A. 93 (7): 2936–40. doi:10.1073/pnas.93.7.2936. PMID 8610146.  
  • Oettel S, Härtel F, Kober I, et al. (1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes.". Nucleic Acids Res. 25 (12): 2440–7. doi:10.1093/nar/25.12.2440. PMID 9171097.  
  • Moreland RJ, Dresser ME, Rodgers JS, et al. (2000). "Identification of a transcription factor IIIA-interacting protein.". Nucleic Acids Res. 28 (9): 1986–93. doi:10.1093/nar/28.9.1986. PMID 10756201.  
  • Rao DS, Chang JC, Kumar PD, et al. (2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors.". Mol. Cell. Biol. 21 (22): 7796–806. doi:10.1128/MCB.21.22.7796-7806.2001. PMID 11604514.  
  • Hanas JS, Hocker JR, Cheng YG, et al. (2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA.". Gene 282 (1-2): 43–52. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.  
  • Weser S, Riemann J, Seifart KH, Meissner W (2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene.". Nucleic Acids Res. 31 (9): 2408–16. doi:10.1093/nar/gkg345. PMID 12711686.  
  • Pellikainen JM, Ropponen KM, Kataja VV, et al. (2005). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.". Clin. Cancer Res. 10 (22): 7621–8. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.  
  • Paing MM, Johnston CA, Siderovski DP, Trejo J (2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.". Mol. Cell. Biol. 26 (8): 3231–42. doi:10.1128/MCB.26.8.3231-3242.2006. PMID 16581796.  
  • Yamashita A, Takada T, Nemoto K, et al. (2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage.". FEBS Lett. 580 (17): 4121–5. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.  
  • Schwartz B, Melnikova VO, Tellez C, et al. (2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo.". Oncogene 26 (28): 4049–58. doi:10.1038/sj.onc.1210193. PMID 17224907.  
  • Hannay JA, Liu J, Zhu QS, et al. (2007). "Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation.". Mol. Cancer Ther. 6 (5): 1650–60. doi:10.1158/1535-7163.MCT-06-0636. PMID 17513613.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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