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Gallamine: Wikis

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Systematic (IUPAC) name
2,2',2''-[benzene-1,2,3-triyltris(oxy)]tris( N,N-diethylethanamine)
CAS number  ?
65-29-2 (triethiodide)
ATC code M03AC02
PubChem 67425
DrugBank APRD00712
Chemical data
Formula C24H45N3O3
C30H60N3O3+3 · 3 I- (gallamine triethiodide)
Mol. mass 423.633 g/mol
891.529 g/mol (triethiodide)
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?
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Gallamine (Flaxedil) is a non-depolarising muscle relaxant.[1]. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. [2]Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.

Gallamine is commonly used to stabilize muscle contractions during surgical procedures.

It was developed by Daniel Bovet in 1947.[3]


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