From Wikipedia, the free encyclopedia
For
information on how to contribute to the Gene Wiki at Wikipedia,
please see Portal:Gene Wiki.
The Gene Wiki is a project that facilitates
transferring information on human genes to Wikipedia article stubs with the goal of
promoting collaboration and expansion of the articles.[1][2]
Project
goals and scope
Number
of gene articles
The human
genome contains an estimated 20,000–25,000 protein-coding genes.[3]
The goal of the Gene Wiki project is to create seed articles for
every notable human gene. More specifically, notable genes would
include those whose function has been assigned in the peer reviewed
scientific literature. Approximately half of human genes have
assigned function, therefore the total number of articles seeded by
the Gene Wiki project would be expcected to be in the range of
10,000 - 15,000. To date, approximately 9,000 articles have been
created or augmented to included Gene Wiki project content.[4]
Expansion
Once seed articles have been established, the hope and
expectation is that these will be annotated and expanded by editors ranging in
experience from the lay audience to students to professionals and
academics.[1]
Proteins encoded by
genes
The vast majority of genes encode proteins hence understanding the function of a
gene generally requires understanding of the function of the
corresponding protein. In addition to including basic information
about the gene, the project therefore also includes information
about the protein encoded by the gene.
Gene
Wiki generated content
Stubs for the Gene Wiki project are created by a bot and contain links
to the following primary gene/protein databases:
See also
References
- ^ a
b
Huss JW, Orozco C, Goodale J, Wu C,
Batalov S, Vickers TJ, Valafar F, Su AI (July 2008). "A Gene Wiki for Community
Annotation of Gene Function". PLoS Biol.
6 (7): e175. doi:10.1371/journal.pbio.0060175. PMID 18613750.
- ^ Huss JW, Orozco C, Goodale J, Wu C, Batalov S,
Vickers TJ, Valafar F, Su AI. "SciVee Pubcast: A Gene Wiki for Community
Annotation of Gene Function". http://www.scivee.tv/pubcast/18613750. Retrieved
2008-11-19.
- ^ Clamp M, Fry B, Kamal M, Xie X, Cuff J,
Lin MF, Kellis M, Lindblad-Toh K, Lander ES (December 2007). "Distinguishing
protein-coding and noncoding genes in the human genome".
Proc. Natl. Acad. Sci. U.S.A. 104 (49):
19428–33. doi:10.1073/pnas.0709013104. PMID 18040051.
- ^ "Gene Wiki Pages". Pages that link to
Template:PBB Controls. Wikipedia, the free encyclopedia.
http://en.wikipedia.org/w/index.php?offset=&limit=500&target=Template%3APBB_Controls&title=Special%3AWhatlinkshere&namespace=0. Retrieved
2008-07-19.
- ^ Su AI, Wiltshire T, Batalov S, Lapp H,
Ching KA, Block D, Zhang J, Soden R, Hayakawa M, Kreiman G, Cooke
MP, Walker JR, Hogenesch JB (April 2004). "A gene atlas of the mouse
and human protein-encoding transcriptomes". Proc. Natl.
Acad. Sci. U.S.A. 101 (16): 6062–7. doi:10.1073/pnas.0400782101. PMID 15075390.
External
links