From Wikipedia, the free encyclopedia
- The native form of this personal name is Békésy
György. This article uses the Western name order.
Georg von Békésy (Békésy György) (June 3, 1899
– June 13, 1972) was a Hungarian biophysicist born in Budapest.
In 1961, he was awarded the Nobel Prize in
Physiology or Medicine for his research on the function of the
cochlea in the mammalian
hearing organ. The decision of the prize committee had been
controversial from the beginning, and research of the past three
decades revealed that von Békésy’s main conclusions were in
error.
Research
Békésy developed a method for dissecting the inner ear of human
cadavers while leaving the
cochlea partly intact. By using strobe photography and silver flakes as a marker, he was able to
observe that the basilar membrane moves like a surface wave when
stimulated by sound. Because of
the structure of the cochlea and the basilar membrane, different frequencies of sound cause
the maximum amplitudes of the waves to occur at different places on
the basilar membrane along the coil of the cochlea.[1]
He concluded that his observations showed how different sound
wave frequencies are locally dispersed before exciting different nerve
fibers that lead from the cochlea to the brain. He theorized
that the placement of each sensory cell (hair cell) along the coil of the cochlea
corresponds to a specific frequency of sound (the so-called tonotopy). Békésy later
developed a mechanical model of the cochlea, which confirmed the
concept of frequency dispersion by the basilar membrane in the
mammalian cochlea. But this model could not provide any information
as to a possible function of this frequency dispersion in the
process of hearing.[1]
In a posthumous 1974 article looking back over progress in the
field, he remarked "In time, I came to the conclusion that the
dehydrated cats and the application of Fourier analysis to hearing problems
became more and more a handicap for research in hearing,"[2]
referring to the difficulties in getting animal preparations to
behave as when alive, and the misleading common interpretations of
Fourier analysis in hearing research.
Biography
Békésy was born in Budapest, Hungary, the son of diplomat Alexander von
Békésy and his wife Paula. He went to school in Budapest, Munich, and Zürich. He studied chemistry in Berne and
received his PhD from the University of Budapest in
1926.
During World War
II, Békésy worked for the Hungarian Post Office, where he did
research on telecommunications. This research led him to become
interested in the workings of the ear. In 1946, he left Hungary to
follow this line of research at the Karolinska
Institute in Sweden.
In 1947, he moved to the United States, working at Harvard
University until 1966. He became a professor at the University of Hawaii in 1966 and
died in Honolulu.
References
Further
reading
- Czeizel, Andrew
E (2004), "Famous Hungarian physicians", The Lancet
364 (9434): 581–2, doi:10.1016/S0140-6736(04)16847-5, PMID 15195664
- Evans, Rand B
(2003), "Georg von Békésy: visualization of hearing", American
Psychologist 58 (9): 742–6, 2003 Sep, doi:10.1037/0003-066X.58.9.742, PMID 14584991
- Raju, T N (1999),
"The Nobel chronicles. 1961: Georg von Békésy (1899-1972)", Lancet
354 (9172): 80, 1999 Jul 3, doi:10.1016/S0140-6736(05)75353-8, PMID 10406402
- Shampo, M A;
Kyle, R A (1993), "Georg von Békésy--audiology and the cochlea",
Mayo Clin. Proc. 68 (7): 706, 1993 Jul,
PMID 8350644
- Tonndorf, J
(1986), "Georg von Békésy and his work", Hear. Res.
22: 3–10, doi:10.1016/0378-5955(86)90067-5, PMID 3525485
- Bernhard, C G
(1986), "Georg von Békésy and the Karolinska Institute", Hear.
Res. 22: 13–7, doi:10.1016/0378-5955(86)90069-9, PMID 3525483
- "Proceedings of Nobel Symposium 63.
Cellular mechanisms in hearing (en hommage à Georg von Békésy).
Karlskoga, 2–6 September 1985", Hear. Res.
22: 1–326, 1986, PMID 3525481
- Tonndorf, J
(1974), "In memoriam Georg von Békésy 1899-1972", J. Acoust.
Soc. Am. 55 (3): 576–7, 1974 Mar, doi:10.1121/1.1914566,
PMID 4594785
- Glorig, A (1973),
"Georg von Békésy 1899-1972", Audiology
12 (5): 540–1, doi:10.3109/00206097309071667, PMID 4582926
- Keidel, W D
(1973), "In memorian Professor Dr. phil. Dr. med. h.c. Georg v.
Békésy", Kybernetik 12 (2): 116–8, 1973
Feb, doi:10.1007/BF00272468, PMID 4571620
- Ratliff, F
(1973), "Georg von Békésy", Experimental brain research.
Experimentelle Hirnforschung. Expérimentation cérébrale
16 (3): 219–20, 1973 Jan 29, PMID 4568685
- Keidel, W D
(1973), "[In memoriam Professor Dr.phil.Dr.med.h.c. Georg von
Békésy]", Zeitschrift für Laryngologie, Rhinologie, Otologie
und ihre Grenzgebiete 52 (1): 1–6, 1973 Jan,
PMID 4567951
- Davis, H (1972),
"Georg von Békésy, 1899-1972", Ann. Otol. Rhinol.
Laryngol. 81 (5): 750–1, 1972 Oct, PMID 4568444
- Zwislocki, J J
(1972), "Georg von Békésy, 1899-1972", J. Acoust. Soc. Am.
52 (4): 1094–5, 1972 Oct, PMID 4563147
- "Georg von Beksey", ASHA
14 (9): 513, Sep 1972, 1972 Sep, ISSN 0001-2475, PMID 4560564
- Tonndorf, J
(1972), "[Obituary for Georg von Békésy (1899-1972)]", Archiv
für klinische und experimentelle Ohren- Nasen- und
Kehlkopfheilkunde 203 (1): 81–5, doi:10.1007/BF00344566, PMID 4564741
- "The American Speech and Hearing
Association presents the honors of the Association", ASHA
9 (6): 222, 1967, 1967 Jun, PMID 5343023
- BERNHARD, C G
(1962), "Presentation of the Nobel prize for physiology or medicine
(1961) to George von BEKESY", Transactions of the American
Otological Society 50: 332–6, PMID 13971073
- KEIDEL, W D
(1961), "[G. von BEKESY Nobel prize winner 1961.]", Zeitschrift
für Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete
40: 885–8, 1961 Dec, PMID 14037041
- PALVA, T (1961),
"[The 1961 Nobel prize in medical science and physiology (Georg von
BEKESY).]", Duodecim; lääketieteellinen aikakauskirja
77: 791–2, PMID 14037251
External
links
See also: Békésy