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Glycine transporter 1: Wikis


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From Wikipedia, the free encyclopedia

Solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Symbols SLC6A9; GLYT1; DKFZp547A1118
External IDs OMIM601019 MGI95760 HomoloGene5050 GeneCards: SLC6A9 Gene
RNA expression pattern
PBB GE SLC6A9 207043 s at tn.png
More reference expression data
Species Human Mouse
Entrez 6536 14664
Ensembl ENSG00000196517 ENSMUSG00000028542
UniProt P48067 P28571
RefSeq (mRNA) NM_001024845 NM_008135
RefSeq (protein) NP_001020016 NP_032161
Location (UCSC) Chr 1:
44.23 - 44.27 Mb
Chr 4:
117.33 - 117.37 Mb
PubMed search [1] [2]

Sodium- and chloride-dependent glycine transporter 1 is a protein that in humans is encoded by the SLC6A9 gene.[1][2][3]

See also


  1. ^ Kim KM, Kingsmore SF, Han H, Yang-Feng TL, Godinot N, Seldin MF, Caron MG, Giros B (Jun 1994). "Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes". Mol Pharmacol 45 (4): 608-17. PMID 8183239.  
  2. ^ Jones EM, Fernald A, Bell GI, Le Beau MM (Nov 1995). "Assignment of SLC6A9 to human chromosome band 1p33 by in situ hybridization". Cytogenet Cell Genet 71 (3): 211. PMID 7587377.  
  3. ^ "Entrez Gene: SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9".  

Further reading

  • Olivares L, Aragón C, Giménez C, Zafra F (1995). "The role of N-glycosylation in the targeting and activity of the GLYT1 glycine transporter.". J. Biol. Chem. 270 (16): 9437–42. doi:10.1074/jbc.270.16.9437. PMID 7721869.  
  • Borowsky B, Mezey E, Hoffman BJ (1993). "Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.". Neuron 10 (5): 851–63. doi:10.1016/0896-6273(93)90201-2. PMID 8494645.  
  • Evans J, Herdon H, Cairns W, et al. (2000). "Cloning, functional characterisation and population analysis of a variant form of the human glycine type 2 transporter.". FEBS Lett. 463 (3): 301–6. doi:10.1016/S0014-5793(99)01636-1. PMID 10606742.  
  • Hanley JG, Jones EM, Moss SJ (2000). "GABA receptor rho1 subunit interacts with a novel splice variant of the glycine transporter, GLYT-1.". J. Biol. Chem. 275 (2): 840–6. doi:10.1074/jbc.275.2.840. PMID 10625616.  
  • Geerlings A, López-Corcuera B, Aragón C (2000). "Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A.". FEBS Lett. 470 (1): 51–4. doi:10.1016/S0014-5793(00)01297-7. PMID 10722844.  
  • Christie GR, Ford D, Howard A, et al. (2001). "Glycine supply to human enterocytes mediated by high-affinity basolateral GLYT1.". Gastroenterology 120 (2): 439–48. doi:10.1053/gast.2001.21207. PMID 11159884.  
  • Reye P, Penfold P, Pow DV (2001). "Glyt-1 expression in cultured human Müller cells and intact retinae.". Glia 34 (4): 311–5. doi:10.1002/glia.1064. PMID 11360303.  
  • Geerlings A, Núñez E, Rodenstein L, et al. (2002). "Glycine transporter isoforms show differential subcellular localization in PC12 cells.". J. Neurochem. 82 (1): 58–65. doi:10.1046/j.1471-4159.2002.00930.x. PMID 12091465.  
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.  
  • Antonov SM, Brovtsyna NB, Mironova EV (2005). "The mechanism of allosteric interaction of cytoplasmic and extracellular Cl- in the glial glycine transporter (hGlyTlb).". Dokl. Biol. Sci. 402: 163–6. doi:10.1007/s10630-005-0076-z. PMID 16121932.  


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