The Full Wiki

More info on Granule (cell biology)

Granule (cell biology): Wikis

Advertisements
  

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

In cell biology, a granule can be any structure barely visible by light microscopy. The term is most often used to describe a secretory vesicle.

Contents

Leukocytes

A group of leukocytes called granulocytes contain granules and play an important role in the immune system. The granules of certain cells, such as natural killer cells, contain components which can lead to the lysis of neighboring cells. The granules of leukocytes are classified as azurophilic granules or specific granules. Leukocyte granules are released in response to immunological stimuli during a process known as degranulation.

Platelets

The granules of platelets are classified as dense granules and alpha granules.

Germline Granules

In 1957, André and Rouiller first coined the term "nuage" (French for "cloud"). Its amorphous and fibrous structure occurred in drawings as early as in 1933 (Risley 1933). Today, the nuage is accepted to represent a characteristic, electrondense germ plasm organelle encapsulating the cytoplasmic face of the nuclear envelope of the cells destined to the germline fate. The same granular material is also known under various synonyms: dense bodies, mitochondrial clouds, yolk nuclei, Balbiani bodies, perinulcear P granules in Caenorhabditis elegans, germinal granules in Xenopus laevis and chromatoid body in mouse and polar granules in Drosophila. Molecularly, the nuage is a tightly interwoven network of differentially localized RNA-binding proteins, which in turn localize specific mRNA species for differential storage, asymmetric segregation (as needed for asymmetric cell division), differential splicing and/or translational control. The germline granules appear to be ancestral and universally conserved in the germlines of all metazoan phyla.

See also

External links

Advertisements

Simple English

In cell biology, a granule can be any structure barely visible by light microscopy. The term is most often used to describe a secretory vesicle.

Leukocytes

A group of leukocytes called granulocytes contain granules and play an important role in the immune system. The granules of certain cells, such as Natural Killer Cells, contain components which can lead to the lysis of neighboring cells.

Platelets

The granules of platelets are classified as dense granules and alpha granules.


Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message