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Gut-associated lymphoid tissue: Wikis

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From Wikipedia, the free encyclopedia

The digestive tract's immune system is often referred to as gut-associated lymphoid tissue (GALT) and works to protect the body from invasion. GALT is an example of mucosa-associated lymphoid tissue.

Contents

Function

About 70% of the body's immune system is found in the digestive tract. The GALT is made up of several types of lymphoid tissue that store immune cells, such as T and B lymphocytes, that carry out attacks and defend against pathogens.

New research indicates that GALT may continue to be a major site of HIV activity, even if drug treatment has reduced HIV count in the peripheral blood.[1][2]

Components

Lymphoid tissue in the gut comprises the following:

Additional images

References

  1. ^ Moraima Guadalupe,1 Sumathi Sankaran,1 Michael D. George,1 Elizabeth Reay,1 David Verhoeven,1 Barbara L. Shacklett,1 Jason Flamm,4 Jacob Wegelin,3 Thomas Prindiville,2 and Satya Dandekar. Viral Suppression and Immune Restoration in the Gastrointestinal Mucosa of HIV Type 1-Infected Patients Initiating Therapy during Primary or Chronic Infection Journal of Virology, August 2006, p. 8236-8247, Vol. 80, No. 16
  2. ^ Anton PA, Mitsuyasu RT, Deeks SG, Scadden DT, Wagner B, Huang C, Macken C, Richman DD, Christopherson C, Borellini F, Lazar R, Hege KM. Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects. AIDS. 2003 Jan 3;17(1):53-63.

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