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HTR3E: Wikis


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From Wikipedia, the free encyclopedia

5-hydroxytryptamine (serotonin) receptor 3, family member E
Symbols HTR3E; MGC120035; MGC120037; MGC120036
External IDs OMIM610123 HomoloGene50735 IUPHAR: 5-HT3E GeneCards: HTR3E Gene
Species Human Mouse
Entrez 285242 n/a
Ensembl ENSG00000186038 n/a
UniProt n/a n/a
RefSeq (mRNA) NM_182589 n/a
RefSeq (protein) NP_872395 n/a
Location (UCSC) Chr 3:
185.3 - 185.31 Mb
PubMed search [1] n/a

5-hydroxytryptamine receptor 3E is a protein that in humans is encoded by the HTR3E gene.[1][2][1] The protein encoded by this gene is a subunit of the 5-HT3 receptor.[2]


  1. ^ a b Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene 310: 101-11. PMID 12801637.  
  2. ^ a b Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans 32 (Pt3): 547-52. doi:10.1042/BST0320547. PMID 15157181.  

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Karnovsky AM, Gotow LF, McKinley DD, et al. (2003). "A cluster of novel serotonin receptor 3-like genes on human chromosome 3.". Gene 319: 137-48. PMID 14597179.  
  • Nalivaiko E, Sgoifo A (2009). "Central 5-HT receptors in cardiovascular control during stress.". Neuroscience and biobehavioral reviews 33 (2): 95-106. doi:10.1016/j.neubiorev.2008.05.026. PMID 18573276.  
  • Kapeller J, Houghton LA, Mönnikes H, et al. (2008). "First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome.". Hum. Mol. Genet. 17 (19): 2967-77. doi:10.1093/hmg/ddn195. PMID 18614545.  

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