|Time of origin||107,600–174,300 YBP|
|Place of origin||East Africa|
|Defining mutations||3666, 7055, 7389, 13789, 14178, 14560 |
In human mitochondrial genetics, Haplogroup L1 is a human mitochondrial DNA (mtDNA) haplogroup and major subclade of Haplogroup L (mtDNA). Though it is typically used to refer to a family of lineages found in Africa, L1 is sometimes referred to as haplogroup L1-6, which is the macrohaplogroup that includes the majority of African lineages and all non-African lineages. Haplogroup L1-6 is is the macrohaplogroup that includes subclades L2, L3, L5, L6, and also L3 which gave rise to the two non-African haplogroups M and N. Haplogroup L1 is therefore the paragroup of haplogroup L1-6. Haplogroup L1 and its only sibling haplogroup L0 are united by the matrilineal most recent common ancestor, (MRCA) of all living humans, Mitochondrial Eve. The existence of these two lineages, implies that Mitochondrial Eve had at least two daughters, one of whom is the maternal common ancestor of haplogroup L1 lineages.
Haplogroup L1 is believed to have first appeared in East Africa approximately 150,000 to 170,000 years ago. Haplogroup L1 is a daughter of Mitochondrial Eve like haplogroup L0. L1 and sisters haplogroups L2, L3, L4, L5, and L6 are distinguished from L0 by the genetic marker changes at 182, 1048, 4312, 6185, 11914, and 12007.
L1 has two branches:
The formerly named L1 branches (L1d, L1k, L1a, L1f) have been re-classified into haplogroup L0 as L0d, L0k, L0a and L0f.
This phylogenetic tree of haplogroup L1 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.
|Mitochondrial Eve (L)|
|H||V||J||T||Former Clusters IWX|
Haplogroup L1 is found in West and Central sub-Saharan Africa. Some of its branches (L1d, L1k, L1a, L1f) were recently re-classified into haplogroup L0 as L0d, L0k, L0a and L0f.
Haplogroup L1 is believed to have first appeared in Africa approximately 150,000 to 170,000 years ago.
|most recent common mt-ancestor|
|This page uses content from the English language Wikipedia. The original content was at Haplogroup L1 (mtDNA). The list of authors can be seen in the page history. As with this Familypedia wiki, the content of Wikipedia is available under the Creative Commons License.|