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Sphincter of Oddi
Interior of the descending portion of the duodenum, showing bile papilla.
MeSH Oddi's+Sphincter

The Sphincter of Oddi is a muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi.[1] The Sphincter of Oddi is relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[2]

Clinical significance


  1. ^ synd/2709 at Who Named It?
  2. ^ J Clin Invest. 1988 June; 81(6): 1920–1924.
  • Gray's Anatomy, 39th ed. p. 1228.

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