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Hetacillin: Wikis


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Systematic (IUPAC) name
CAS number  ?
ATC code J01CA18
PubChem 3596
Chemical data
Formula C 19H23N3O4S 
Mol. mass 389.46862
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Hetacillin is a beta-lactam. Hetacillin is a prodrug and it has no intrinsic antibacterial activity, but is converted by the body to ampicillin, which is active against a variety of organisms.


Hetacillin is administered orally. The potassium salt, hetacillin potassium, is administered by injection, either intravenously or intramuscularly.

Hetacillin was removed from the market for human use when the discovery was made that it is actually cleaved in the GI tract to formaldehyde and had no benefit to non-ester derivatives (i.e. Ampicillin).



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