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Hexetidine
Systematic (IUPAC) name
1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidin-5-amine
Identifiers
CAS number 141-94-6
ATC code A01AB12
PubChem 3607
Chemical data
Formula C 21H45N3  
Mol. mass 339.602 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat. Not to be used by pregnant women.
Legal status
Routes Topical (mouthwash)

Hexetidine (Latin: Hexetidinum) is an anti-bacterial and anti-fungal agent commonly used in both veterinary and human medicine. It is a local anesthetic, astringent and deodorant and has antiplaque effects.[1][2]

Hexetidine is the medicinal ingredient in Sterisol, which is labelled for "the symptomatic treatment of 'strep' throat, tonsillitis, pharyngitis, laryngitis, gingivitis, ulcerative stomatitis, oral thrush and Vincent's angina; postoperative hygiene following tonsillectomy, throat or oral surgery."

In the UK, Hexetidine is the active ingredient in the medicated mouthwash branded Oraldene. This is produced by Pfizer. Oraldene mouthwash contains 0.1g/100ml of Hexetidine. In some European countries, the gargle solution and mouth spray in bottles of 40ml named "Hexoral" (by Pfizer) also contains 0.2% Hexetidine as its active compound. Hexetidine can also be found in the mouthwash "Bactidol" (by Pfizer) which is sold in many Asian countries.

External links

References

  1. ^ Kapić E, Becić F, Becić E (2002). "Hexetidine--an oral antiseptic". Med Arh 56 (1): 43–8. PMID 11917691.  
  2. ^ "Oraldene". NetDoctor.co.uk. July 8, 2004. http://www.netdoctor.co.uk/medicines/100001942.html. Retrieved 2007-04-03.  
Hexetidine







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