The Full Wiki

More info on Human ewingii ehrlichiosis

Human ewingii ehrlichiosis: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

(Redirected to Ehrlichiosis ewingii infection article)

From Wikipedia, the free encyclopedia

Human ewingii ehrlichiosis
Classification and external resources
eMedicine med/3391 ped/655 emerg/159

Ehrlichiosis ewingii infection[1] is an infectious disease caused by an intracellular bacteria, Ehrlichia ewingii.[2] The infection is transmitted to humans by Amblyomma americanum. This tick can also transmit Ehrlichia chaffeensis, the bacteria that causes Human monocytic ehrlichiosis (HME).

Contents

Mechanism of Illness

Humans contract the disease after a bite by an infected tick of the species Amblyomma americanum.

Those with an underlying immunodeficiency (such as HIV) appear to be at greater risk of contracting the disease. Compared to HME, ewingii ehrlichiosis has a decreased incidence of complications.[3]

Like Anaplasma phagocytophilum, the causative agent of human granulocytic ehrlichiosis, Ehrlichia ewingii infects neutrophils. Infection with E. ewingii may delay neutrophil apoptosis.[4]

Symptoms

Patients can present with fever, headache, myalgias, and malaise. Laboratory tests may reveal thrombocytopenia, leukopenia, and evidence of liver damage.

Diagnosis

In endemic areas, a high index of suspicion is warranted, especially with a known exposure to ticks. The diagnosis can be confirmed by using PCR.[5] A peripheral blood smear can also be examined for intracytoplasmic inclusions called morulae.

Treatment

The treatment of choice is doxycycline.

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1130. ISBN 1-4160-2999-0.  
  2. ^ Patnaik MM (June 2009). "Inclusion bodies in tick-borne diseases diagnosed in patients from northern Wisconsin". Clin Med Res 7 (1-2): 45–7. doi:10.3121/cmr.2009.807.818. PMID 19574488. PMC 2705270. http://www.clinmedres.org/cgi/pmidlookup?view=long&pmid=19574488.  
  3. ^ Paddock CD, Folk SM, Shore GM, et al. (November 2001). "Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in persons coinfected with human immunodeficiency virus". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 33 (9): 1586–94. doi:10.1086/323981. PMID 11568857. http://www.journals.uchicago.edu/cgi-bin/resolve?CID010310.  
  4. ^ Xiong Q, Bao W, Ge Y, Rikihisa Y (April 2008). "Ehrlichia ewingii infection delays spontaneous neutrophil apoptosis through stabilization of mitochondria". The Journal of infectious diseases 197 (8): 1110–8. doi:10.1086/533457. PMID 18462160.  
  5. ^ Gusa, Aa; Buller, Rs; Storch, Ga; Huycke, Mm; MacHado, Lj; Slater, Ln; Stockham, Sl; Massung, Rf (Nov 2001). "Identification of a p28 gene in Ehrlichia ewingii: evaluation of gene for use as a target for a species-specific PCR diagnostic assay." (Free full text). Journal of clinical microbiology 39 (11): 3871–6. doi:10.1128/JCM.39.11.3871-3876.2001. PMID 11682500. PMC 88457. http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=11682500.  
Advertisements

Human ewingii ehrlichiosis
Classification and external resources
eMedicine med/3391  ped/655 emerg/159

Human ewingii ehrlichiosis is an infectious disease caused by an intracellular bacteria, Ehrlichia ewingii. The infection is transmitted to humans by Amblyomma americanum. This tick can also transmit Ehrlichia chaffeensis, the bacteria that causes Human monocytic ehrlichiosis (HME).

Contents

Mechanism of Illness

Humans contract the disease after a bite by an infected tick of the species Amblyomma americanum.

Those with an underlying immunodeficiency (such as HIV) appear to be at greater risk of contracting the disease. Compared to HME, ewingii ehrlichiosis has a decreased incidence of complications.[1]

Like Anaplasma phagocytophilum, the causative agent of human granulocytic ehrlichiosis, Ehrlichia ewingii infects neutrophils. Infection with E. ewingii may delay neutrophil apoptosis.[2]

Symptoms

Patients can present with fever, headache, myalgias, and malaise. Laboratory tests may reveal thrombocytopenia, leukopenia, and evidence of liver damage.

Diagnosis

In endemic areas, a high index of suspicion is warranted, especially with a known exposure to ticks. The diagnosis can be confirmed by using PCR.[3] A peripheral blood smear can also be examined for intracytoplasmic inclusions called morulae.

Treatment

The treatment of choice is doxycycline.

See also

References

  1. Paddock CD, Folk SM, Shore GM, et al. (November 2001). "Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in persons coinfected with human immunodeficiency virus". Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 33 (9): 1586–94. doi:10.1086/323981. PMID 11568857. http://www.journals.uchicago.edu/cgi-bin/resolve?CID010310. 
  2. Xiong Q, Bao W, Ge Y, Rikihisa Y (April 2008). "Ehrlichia ewingii infection delays spontaneous neutrophil apoptosis through stabilization of mitochondria". The Journal of infectious diseases 197 (8): 1110–8. doi:10.1086/533457. PMID 18462160. 
  3. Gusa, Aa; Buller, Rs; Storch, Ga; Huycke, Mm; Machado, Lj; Slater, Ln; Stockham, Sl; Massung, Rf (Nov 2001). "Identification of a p28 gene in Ehrlichia ewingii: evaluation of gene for use as a target for a species-specific PCR diagnostic assay." (Free full text). Journal of clinical microbiology 39 (11): 3871–6. doi:10.1128/JCM.39.11.3871-3876.2001. PMID 11682500. PMC: 88457. http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=11682500. 

Template:Bacterial diseases


Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message