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Hypogammaglobulinemia: Wikis


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Classification and external resources
ICD-10 D80.0-D80.1
ICD-9 279.00
DiseasesDB 6426
MedlinePlus 001307
eMedicine med/1120 ped/54
MeSH D000361

Hypogammaglobulinemia is a type of immune disorder characterized by a reduction in all types of gamma globulins.[1]

It is distinguished from dysgammaglobulinemia, which is a reduction in some types of gamma globulins, but not others.[2][3]

It is largely synonymous with "agammaglobulinemia". When this term is used (as in "X-linked agammaglobulinemia") it implies that gamma globulins are not merely reduced, but completely absent. Modern assays have allowed most agammaglobulinemias to be more precisely defined as hypogammaglobulinemias,[4] but the distinction is not usually clinically relevant.

Hypogammaglobulinemia is a characteristic of common variable immunodeficiency.[5]


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