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Iclazepam: Wikis


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Systematic (IUPAC) name
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-1,3-dihydro-2 H-1,4-benzodiazepin-2-one
CAS number 57916-70-8
ATC code none
PubChem 68777
Chemical data
Formula C 21H21ClN2O2  
Mol. mass 368.857
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Iclazepam (Clazepam) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide.

Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N1 nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N-(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.[1]

See also


  1. ^ Giudicelli JF, Berdeaux A, Idrissi N, Richer C. Clazepam: pharmacokinetics and effects on performance. British Journal of Clinical Pharmacology. 1978 Jan;5(1):65-9.


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