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Immune disorder
Classification and external resources
ICD-10 D80.-D89.
ICD-9 273, 279
MeSH D007154

An immune disorder is a dysfunction of the immune system. These disorders can be characterized in several different ways:

  • By the component(s) of the immune system affected
  • By whether the immune system is overactive or underactive
  • By whether the condition is congenital or acquired

According to the International Union of Immunological Societies, more than 150 primary immunodeficiency diseases (PIDs) have been characterized.[1] However, the number of acquired immunodeficiencies exceeds the number of PIDs.[2]

It has been suggested that most people have at least one primary immunodeficiency.[3] Due to redundancies in the immune system, though, many of these are never detected.

See also


  1. ^ Geha RS, Notarangelo LD, Casanova JL, et al. (October 2007). "Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee". J. Allergy Clin. Immunol. 120 (4): 776–94. doi:10.1016/j.jaci.2007.08.053. PMID 17952897.  
  2. ^ Kumar A, Teuber SS, Gershwin ME (2006). "Current perspectives on primary immunodeficiency diseases". Clin. Dev. Immunol. 13 (2-4): 223–59. doi:10.1080/17402520600800705. PMID 17162365.  
  3. ^ Casanova JL, Abel L (August 2007). "Primary immunodeficiencies: a field in its infancy". Science (journal) 317 (5838): 617–9. doi:10.1126/science.1142963. PMID 17673650.  

External links



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