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Impromidine: Wikis


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Systematic (IUPAC) name
N-[3-(1H-imidazol-4-yl)-propyl]- N'-(2-{[(4-methyl-1H-imidazol-5-yl)methyl]thio}ethyl)guanidine
CAS number 55273-05-7
ATC code none
PubChem 41376
Chemical data
Formula C 14H23N7S 
Mol. mass 321.44 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Impromidine (INN) is a highly potent and specific histamine H2 receptor agonist.[1]

It has been used diagnostically as a gastric secretion indicator.

See Histamine agonists.


  1. ^ Durant G, Duncan W, Ganellin C, Parsons M, Blakemore R, Rasmussen A (1978). "Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors". Nature 276 (5686): 403–5. doi:10.1038/276403a0. PMID 714166.  


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