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Indanylaminopropane: Wikis


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1 : 1 mixture (racemate)
Systematic (IUPAC) name
CAS number 152624-02-7
ATC code none
PubChem 192600
Chemical data
Formula C 12H17N 
Mol. mass 175.27 g/mol
SMILES eMolecules & PubChem
Synonyms (±)-5-(2-aminopropyl)-2,3-dihydro-1H-indene;
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral

Indanylaminopropane (IAP), sometimes incorrectly referred to as indanylamphetamine, [1] is a psychoactive drug and research chemical of the aminoindane chemical class which has similar effects to those of the substituted methylenedioxyphenethylamine (MDxx) series of compounds. [1] It acts as a non-neurotoxic releasing agent of serotonin, norepinephrine, and dopamine,[2][3] purportedly with catecholamine equilibrium dissociation constants approximately between those of methylenedioxymethamphetamine (MDMA; "Ecstasy") and methylbenzodioxolylbutanamine (MBDB; "Eden") in comparison to serotonin. On account of its significantly greater capacity for releasing serotonin over dopamine, indanylaminopropane is considerably less reinforcing or euphoric than the mainstream MDxx compounds like MDMA; however, in combination with amphetamine, it is said to be virtually indistinguishable from methylenedioxyamphetamine (MDA) by recreational users.

See also


  1. ^ a b Casale JF, McKibben TD, Bozenko JS, Hays PA (2005). "Characterization of the "Indanylamphetamines"". Microgram Journal 3 (1-2): 3–10.  
  2. ^ Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE (March 1998). "Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)". Journal of Medicinal Chemistry 41 (6): 1001–5. doi:10.1021/jm9705925. PMID 9526575.  
  3. ^ Monte AP, Marona-Lewicka D, Cozzi NV, Nichols DE (November 1993). "Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine". Journal of Medicinal Chemistry 36 (23): 3700–6. doi:10.1021/jm00075a027. PMID 8246240.  

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