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Interleukin-12 receptor: Wikis


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interleukin 12 receptor, beta 1
Symbol IL12RB1
Alt. symbols IL12RB, CD212
Entrez 3594
HUGO 5971
OMIM 601604
RefSeq NM_005535
UniProt P42701
Other data
Locus Chr. 19 p13.1
beta 2 subunit, interleukin 12 receptor, beta 2
Symbol IL12RB2
Entrez 3595
HUGO 5972
OMIM 601642
RefSeq NM_001559
UniProt Q99665
Other data
Locus Chr. 1 p31.3-31.2

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12. It consists of beta 1[1] and beta 2 subunits.[2]


  1. ^ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. PMID 7911493.  
  2. ^ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–7. doi:10.1073/pnas.93.24.14002. PMID 8943050.  

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