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Interleukin-28 receptor: Wikis


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interleukin 28 receptor, alpha (interferon, lambda receptor)
Symbol IL28RA
Alt. symbols CRF2/12, IFNLR, IL-28R1
Entrez 163702
HUGO 18584
OMIM 607404
RefSeq NM_170743
UniProt Q8IU57
Other data
Locus Chr. 1 p36.11
interleukin 10 receptor, beta
Symbol IL10RB
Alt. symbols CRFB4, D21S58, D21S66
Entrez 3588
HUGO 5965
OMIM 123889
RefSeq NM_000628
UniProt Q08334
Other data
Locus Chr. 21 q22.1-22.2

Interleukin-28 receptor is a type II cytokine receptor. It binds interleukin-28. It consists of an α and shares a common β subunit the with interleukin-10 receptor.[1][2]


  1. ^ Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP (2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): 69–77. doi:10.1038/ni875. PMID 12483210.  
  2. ^ Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM (2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63–8. doi:10.1038/ni873. PMID 12469119.  

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