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Intestinal epithelium: Wikis


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Simple columnar epithelium.

The intestinal epithelium is the epithelium that covers the small and large intestine. It is simple columnar and nonciliated.

They primarily take part in the digestive system. However, they also express TLR 4 receptors,[1] and are thus a part of the immune system, both as a barrier and as a first-line pathogen recognition system. The mammalian intestine is covered by a single layer of epithelial cells that is renewed every 4–5 days.[2]

Epithelial cells in the small intestine are a type of brush border cell that are joined together by tight junctions to form a polymer impermeable membrane. These cells have a brush border surface to increase their absorptive surface area, thus making them more efficient.


  1. ^ Lippincott's Illustrated Reviews: Immunology. Paperback: 384 pages. Publisher: Lippincott Williams & Wilkins; (July 1, 2007). Language: English. ISBN 0781795435. ISBN 978-0781795432. Page 17
  2. ^ Clevers, Hans. "Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium". Annual Review of Physiology 71: 241–260. doi:10.1146/annurev.physiol.010908.163145.  


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