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Iodophenpropit
Iodophenpropit.png
IUPAC name
Other names 1-[3-(3H-imidazol-4-yl)propylthio]-N'-[2-(4-iodophenyl)ethyl]formamidine
Identifiers
CAS number 143407-29-8
PubChem 3035746
MeSH Iodophenpropit
SMILES
Properties
Molecular formula C15H19IN4S
Molar mass 414.30763
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Iodophenpropit is a histamine antagonist which binds selectively to the H3 subtype. Its 125I radiolabelled form is used for mapping the distribution of H3 receptors in the body.[1][2]

References

  1. ^ Jansen FP, Wu TS, Voss HP, Steinbusch HW, Vollinga RC, Rademaker B, Bast A, Timmerman H. Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, [125I]-iodophenpropit, to rat brain. British Journal of Pharmacology. 1994 Oct;113(2):355-62. PMID 7834183
  2. ^ Jansen FP, Mochizuki T, Maeyama K, Leurs R, Timmerman H. Characterization of histamine H3 receptors in mouse brain using the H3 antagonist [125I]iodophenpropit. Naunyn Schmiedebergs Archives of Pharmacology. 2000 Jul;362(1):60-7. PMID 10935534
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