It was the first time that an Acorn "Clone" carried native PCI support or an XScale processor, it also accomplished a number of firsts.
It was the first time substantial changes had been made to the platform since the release of the Risc PC was introduced in 1993. All interim machines had been built on the 7500 SoC which was widely regarded as a single-chip Risc PC. (It incorporated the memory controller, video, sound, IO and CPU logic of a Risc PC, leaving only memory and disc interfacing to be added.)
The presence of PCI and USB capabilities, as well as the retained "podule" bus attracted comparisons to Acorn's aborted Pheobe PC, however such comparisons should be tempered with Pheobe's proposed feature set, which retained VIDC and 26bit mode, and although Pheobe was intended to be capable of SMP configurations, its proposed shipping configuration had been for one SA110 CPU.
Units first went on sale in December 2002.
On 25 September 2008, Castle Technology announced that production of the Iyonix PC had ceased and that new units would no longer be available to order. The company pledged to provide on-going support via the Iyonix website, the dealer network and e-mail.