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potassium voltage-gated channel, subfamily G, member 4
Identifiers
Symbols KCNG4; MGC4558; MGC129609
External IDs OMIM607603 MGI1913983 HomoloGene23553 IUPHAR: Kv6.4 GeneCards: KCNG4 Gene
Orthologs
Species Human Mouse
Entrez 93107 66733
Ensembl ENSG00000168418 ENSMUSG00000045246
UniProt Q8TDN1 Q80XM3
RefSeq (mRNA) NM_172347 NM_025734
RefSeq (protein) NP_597997 NP_080010
Location (UCSC) Chr 16:
82.81 - 82.83 Mb
Chr 8:
122.15 - 122.16 Mb
PubMed search [1] [2]

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.[1][2][1] The protein encoded by this gene is a voltage-gated potassium channel subunit.[2]

References

  1. ^ a b Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A 99 (12): 7986-91. doi:10.1073/pnas.122617999. PMID 12060745.  
  2. ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473-508. doi:10.1124/pr.57.4.10. PMID 16382104.  

Further reading

  • Mederos Y Schnitzler M, Rinné S, Skrobek L, et al. (2009). "Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.". J. Biol. Chem. 284 (7): 4695-704. doi:10.1074/jbc.M808786200. PMID 19074135.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ (2005). "Domain analysis of Kv6.3, an electrically silent channel.". J. Physiol. (Lond.) 568 (Pt 3): 737-47. doi:10.1113/jphysiol.2005.090142. PMID 16096342.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.  

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