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potassium voltage-gated channel, subfamily H (eag-related), member 7
Identifiers
Symbols KCNH7; ERG3; HERG3; MGC45986
External IDs OMIM608169 MGI2159566 HomoloGene13249 IUPHAR: Kv11.3 GeneCards: KCNH7 Gene
Orthologs
Species Human Mouse
Entrez 90134 170738
Ensembl ENSG00000184611 ENSMUSG00000059742
UniProt Q9NS40 A2AUY8
RefSeq (mRNA) NM_173162 NM_133207
RefSeq (protein) NP_150375 NP_573470
Location (UCSC) Chr 2:
162.94 - 163.4 Mb
Chr 2:
62.53 - 63.02 Mb
PubMed search [1] [2]

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene.[1] The protein encoded by this gene is a voltage-gated potassium channel subunit.[1]

References

  1. ^ a b Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev 57 (4): 473-508. doi:10.1124/pr.57.4.10. PMID 16382104.  

Further reading

  • Akhavan A, Atanasiu R, Noguchi T, et al. (2005). "Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization.". J. Cell. Sci. 118 (Pt 13): 2803-12. doi:10.1242/jcs.02423. PMID 15961404.  
  • Ganetzky B, Robertson GA, Wilson GF, et al. (1999). "The eag family of K+ channels in Drosophila and mammals.". Ann. N. Y. Acad. Sci. 868: 356-69. PMID 10414305.  
  • Martínez A, Santiago JL, Cénit MC, et al. (2008). "IFIH1-GCA-KCNH7 locus: influence on multiple sclerosis risk.". Eur. J. Hum. Genet. 16 (7): 861-4. doi:10.1038/ejhg.2008.16. PMID 18285833.  
  • Couturier N, Gourraud PA, Cournu-Rebeix I, et al. (2009). "IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients.". Eur. J. Hum. Genet. 17 (6): 844-7. doi:10.1038/ejhg.2008.259. PMID 19156166.  
  • Bauer CK, Wulfsen I, Schäfer R, et al. (2003). "HERG K(+) currents in human prolactin-secreting adenoma cells.". Pflugers Arch. 445 (5): 589-600. doi:10.1007/s00424-002-0980-0. PMID 12634931.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Wu C, Ma MH, Brown KR, et al. (2007). "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.". Proteomics 7 (11): 1775-85. doi:10.1002/pmic.200601006. PMID 17474147.  

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