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Kruppel-like factor 7 (ubiquitous)
Symbols KLF7; UKLF
External IDs OMIM604865 MGI1935151 HomoloGene2751 GeneCards: KLF7 Gene
RNA expression pattern
PBB GE KLF7 204334 at tn.png
More reference expression data
Species Human Mouse
Entrez 8609 93691
Ensembl ENSG00000118263 ENSMUSG00000025959
UniProt O75840 Q3UES6
RefSeq (mRNA) NM_003709 XM_992457
RefSeq (protein) NP_003700 XP_997551
Location (UCSC) Chr 2:
207.65 - 207.74 Mb
Chr 1:
63.97 - 64.06 Mb
PubMed search [1] [2]

Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a protein which in humans is encoded by the KLF7 gene.[1][2]

This protein is a member of the Kruppel-like family of transcription factors.[3]


  1. ^ "Entrez Gene: KLF7 Kruppel-like factor 7 (ubiquitous)".  
  2. ^ Matsumoto N, Laub F, Aldabe R, Zhang W, Ramirez F, Yoshida T, Terada M (October 1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors". The Journal of Biological Chemistry 273 (43): 28229–37. doi:10.1074/jbc.273.43.28229. PMID 9774444.  
  3. ^ Bieker JJ (September 2001). "Krüppel-like factors: three fingers in many pies". The Journal of Biological Chemistry 276 (37): 34355–8. doi:10.1074/jbc.R100043200. PMID 11443140.  

Further reading

  • Cho SY, Park PJ, Shin HJ, et al. (2007). "(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells.". Am. J. Physiol. Endocrinol. Metab. 292 (4): E1166–72. doi:10.1152/ajpendo.00436.2006. PMID 17164435.  
  • Kawamura Y, Tanaka Y, Kawamori R, Maeda S (2006). "Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line.". Mol. Endocrinol. 20 (4): 844–56. doi:10.1210/me.2005-0138. PMID 16339272.  
  • Kanazawa A, Kawamura Y, Sekine A, et al. (2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.". Diabetologia 48 (7): 1315–22. doi:10.1007/s00125-005-1797-0. PMID 15937668.  
  • Smaldone S, Laub F, Else C, et al. (2004). "Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity.". Mol. Cell. Biol. 24 (3): 1058–69. doi:10.1128/MCB.24.3.1058-1069.2004. PMID 14729953.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Suzuki S, Chuang LF, Doi RH, Chuang RY (2004). "Identification of opioid-regulated genes in human lymphocytic cells by differential display: upregulation of Krüppel-like factor 7 by morphine.". Exp. Cell Res. 291 (2): 340–51. doi:10.1016/S0014-4827(03)00408-7. PMID 14644156.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Matsumoto N, Laub F, Aldabe R, et al. (1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors.". J. Biol. Chem. 273 (43): 28229–37. doi:10.1074/jbc.273.43.28229. PMID 9774444.  

External links



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