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Keliximab: Wikis

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Encyclopedia

From Wikipedia, the free encyclopedia

Keliximab ?
Monoclonal antibody
Source Chimeric
Target CD4
Identifiers
CAS number 174722-30-6
ATC code none
PubChem  ?
Chemical data
Formula  ?
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes intravenous

Keliximab is a chimeric monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4.[1]

References

  1. ^ Kon, OM; Sihra; Compton; Leonard; Kay; Barnes (1998). "Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma". Lancet 352 (9134): 1109–13. doi:10.1016/S0140-6736(97)12261-9. PMID 9798587.  
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