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Ketazocine
Ketazocine.svg
Ketazocine 3D.png
IUPAC name
Identifiers
CAS number 36292-69-0
PubChem 71426
MeSH ketazocine
Properties
Molecular formula C18H23NO2
Molar mass 285.381 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Ketazocine (INN) (Ketocyclazocine) is a cyclazocine derivative used in opioid receptor research. Ketocyclazocine is an exogenous opioid that binds to the kappa opioid receptor.

Activation of this receptor causes a decrease in pain sensations and increased sleepiness but can also cause psychological symptoms such as feelings of unease, paranoia, and hallucinations. It also causes an increase in urine production because it inhibits the release of vasopressin. (Vasopressin is an endogenous substance that assists in regulating fluid and electrolyte balance in the body and decreases the amount of water released into the urine.)

Unlike other opioids, substances that only bind to the kappa receptor theoretically do not impair the normal drive to breathe.

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