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Lysosomal-associated membrane protein 3
External IDs OMIM605883 MGI2441659 HomoloGene8670 GeneCards: LAMP3 Gene
RNA expression pattern
PBB GE LAMP3 205569 at tn.png
More reference expression data
Species Human Mouse
Entrez 27074 239739
Ensembl ENSG00000078081 ENSMUSG00000041247
UniProt Q9UQV4 Q7TST5
RefSeq (mRNA) NM_014398 NM_177356
RefSeq (protein) NP_055213 NP_796330
Location (UCSC) Chr 3:
184.32 - 184.36 Mb
Chr 16:
19.57 - 19.62 Mb
PubMed search [1] [2]

Lysosome-associated membrane glycoprotein 3 is a protein that in humans is encoded by the LAMP3 gene.[1][2]

LAMP3 has also recently been designated CD208 (cluster of differentiation 208).


  1. ^ Ozaki K, Nagata M, Suzuki M, Fujiwara T, Ueda K, Miyoshi Y, Takahashi E, Nakamura Y (Sep 1998). "Isolation and characterization of a novel human lung-specific gene homologous to lysosomal membrane glycoproteins 1 and 2: significantly increased expression in cancers of various tissues". Cancer Res 58 (16): 3499-503. PMID 9721848.  
  2. ^ "Entrez Gene: LAMP3 lysosomal-associated membrane protein 3".  

Further reading

  • de Saint-Vis B, Vincent J, Vandenabeele S, et al. (1998). "A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment.". Immunity 9 (3): 325–36. doi:10.1016/S1074-7613(00)80615-9. PMID 9768752.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Akasaki K, Nakamura N, Tsukui N, et al. (2004). "Human dendritic cell lysosome-associated membrane protein expressed in lung type II pneumocytes.". Arch. Biochem. Biophys. 425 (2): 147–57. doi:10.1016/ PMID 15111122.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Kanao H, Enomoto T, Kimura T, et al. (2005). "Overexpression of LAMP3/TSC403/DC-LAMP promotes metastasis in uterine cervical cancer.". Cancer Res. 65 (19): 8640–5. doi:10.1158/0008-5472.CAN-04-4112. PMID 16204031.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  
  • Arruda LB, Sim D, Chikhlikar PR, et al. (2006). "Dendritic cell-lysosomal-associated membrane protein (LAMP) and LAMP-1-HIV-1 gag chimeras have distinct cellular trafficking pathways and prime T and B cell responses to a diverse repertoire of epitopes.". J. Immunol. 177 (4): 2265–75. PMID 16887987.  
  • Zhu LC, Yim J, Chiriboga L, et al. (2007). "DC-LAMP stains pulmonary adenocarcinoma with bronchiolar Clara cell differentiation.". Hum. Pathol. 38 (2): 260–8. doi:10.1016/j.humpath.2006.07.018. PMID 17056097.  
  • Elliott B, Scolyer RA, Suciu S, et al. (2007). "Long-term protective effect of mature DC-LAMP+ dendritic cell accumulation in sentinel lymph nodes containing micrometastatic melanoma.". Clin. Cancer Res. 13 (13): 3825–30. doi:10.1158/1078-0432.CCR-07-0358. PMID 17606713.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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