The Full Wiki

More info on Lapachol

Lapachol: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

IUPAC name
CAS number 84-79-7
PubChem 3884
Molecular formula C15H14O3
Molar mass 242.27
Appearance Yellow crystals
Melting point

140 °C, 413 K, 284 °F

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Lapachol is a natural organic compound isolated from the lapacho tree (Tabebuia avellandedae).[3] Chemically, it is a derivative of naphthoquinone, related to vitamin K.

Once studied as a possible treatment for some types of cancer, lapachol's potential is now considered low due to its toxic side effects.[4][5][6][7]


  1. ^ [1] Lapochol at R&D Chemicals.
  2. ^ [2] Lapochol at CromaDex.
  3. ^ Record, Samuel J. Lapachol. Tropical Woods (1925), 1 7-9.
  4. ^ Felício AC, Chang CV, Brandão MA, Peters VM, Guerra Mde O (2002). "Fetal growth in rats treated with lapachol". Contraception 66 (4): 289–93. doi:10.1016/S0010-7824(02)00356-6. PMID 12413627.  
  5. ^ Oral toxicology studies with lapachol. Morrison, Robert K.; Brown, Donald Emerson; Oleson, Jerome J.; Cooney, David A. Toxicology and Applied Pharmacology (1970), 17(1), 1-11.
  6. ^ Guerra Mde O, Mazoni AS, Brandão MA, Peters VM (2001). "Toxicology of Lapachol in rats: embryolethality". Brazilian journal of biology = Revista brasleira de biologia 61 (1): 171–4. PMID 11340475.  
  7. ^ de Cássia da Silveira E Sá R, de Oliveira Guerra M (2007). "Reproductive toxicity of lapachol in adult male Wistar rats submitted to short-term treatment". Phytotherapy research : PTR 21 (7): 658–62. doi:10.1002/ptr.2141. PMID 17421057.  


Got something to say? Make a comment.
Your name
Your email address