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Lazabemide: Wikis

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Lazabemide
Systematic (IUPAC) name
N-(2-aminoethyl)-5-chloro-pyridine-2-carboxamide
Identifiers
CAS number  ?
ATC code  ?
PubChem 71307
ChemSpider 64426
Chemical data
Formula C8H10ClN3O
Mol. mass 199.64 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral

Lazabemide (Pakio, Tempium) is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) which is used as an antiparkinsonian agent.[1]

References

  1. ^ Henriot S, Kuhn C, Kettler R, Da Prada M. (1994). "Lazabemide (Ro 19-6327), a reversible and highly sensitive MAO-B inhibitor: preclinical and clinical findings.". J Neural Transm Suppl. 41: 321–325. PMID 7931245.  
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