The Full Wiki

More info on Leukotriene B4 receptor

Leukotriene B4 receptor: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
Leukotriene B4 receptor
Identifiers
Symbols LTB4R; BLT1; BLTR; CMKRL1; GPR16; LTB4R1; LTBR1; P2RY7; P2Y7
External IDs OMIM601531 MGI1309472 HomoloGene22477 IUPHAR: BLT1 GeneCards: LTB4R Gene
Orthologs
Species Human Mouse
Entrez 1241 16995
Ensembl Ensembl:ENSG00000213903 ENSMUSG00000046908
UniProt Q15722 Q3U2P2
RefSeq (mRNA) NM_181657 NM_008519
RefSeq (protein) NP_858043 NP_032545
Location (UCSC) Chr 14:
24.78 - 24.79 Mb
Chr 14:
54.72 - 54.72 Mb
PubMed search [1] [2]

Leukotriene B4 receptor 1 is a protein that in humans is encoded by the LTB4R gene.[1][2][3]

Contents

See also

References

  1. ^ Owman C, Nilsson C, Lolait SJ (Feb 1997). "Cloning of cDNA encoding a putative chemoattractant receptor". Genomics 37 (2): 187-94. doi:10.1006/geno.1996.0541. PMID 8921391.  
  2. ^ Akbar GK, Dasari VR, Webb TE, Ayyanathan K, Pillarisetti K, Sandhu AK, Athwal RS, Daniel JL, Ashby B, Barnard EA, Kunapuli SP (Sep 1996). "Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells". J Biol Chem 271 (31): 18363-7. PMID 8702478.  
  3. ^ "Entrez Gene: LTB4R leukotriene B4 receptor". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1241.  

Further reading

  • Raport CJ, Schweickart VL, Chantry D, et al. (1996). "New members of the chemokine receptor gene family.". J. Leukoc. Biol. 59 (1): 18–23. PMID 8558062.  
  • Tager AM, Luster AD (2004). "BLT1 and BLT2: the leukotriene B(4) receptors.". Prostaglandins Leukot. Essent. Fatty Acids 69 (2-3): 123–34. doi:10.1016/S0952-3278(03)00073-5. PMID 12895595.  
  • Miyahara N, Miyahara S, Takeda K, Gelfand EW (2006). "Role of the LTB4/BLT1 pathway in allergen-induced airway hyperresponsiveness and inflammation.". Allergology international : official journal of the Japanese Society of Allergology 55 (2): 91–7. doi:10.2332/allergolint.55.91. PMID 17075244.  
  • Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.  
  • Yokomizo T, Izumi T, Chang K, et al. (1997). "A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.". Nature 387 (6633): 620–4. doi:10.1038/42506. PMID 9177352.  
  • Maier R, Glatz A, Mosbacher J, Bilbe G (1997). "Cloning of P2Y6 cDNAs and identification of a pseudogene: comparison of P2Y receptor subtype expression in bone and brain tissues.". Biochem. Biophys. Res. Commun. 237 (2): 297–302. doi:10.1006/bbrc.1997.7135. PMID 9268704.  
  • Gaudreau R, Le Gouill C, Métaoui S, et al. (1998). "Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.". Biochem. J. 335 ( Pt 1): 15–8. PMID 9742207.  
  • Kato K, Yokomizo T, Izumi T, Shimizu T (2000). "Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene.". J. Exp. Med. 192 (3): 413–20. doi:10.1084/jem.192.3.413. PMID 10934229.  
  • Yokomizo T, Kato K, Terawaki K, et al. (2000). "A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders.". J. Exp. Med. 192 (3): 421–32. doi:10.1084/jem.192.3.421. PMID 10934230.  
  • Stankova J, Turcotte S, Harris J, Rola-Pleszczynski M (2002). "Modulation of leukotriene B4 receptor-1 expression by dexamethasone: potential mechanism for enhanced neutrophil survival.". J. Immunol. 168 (7): 3570–6. PMID 11907121.  
  • Gaudreau R, Le Gouill C, Venne MH, et al. (2002). "Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.". J. Biol. Chem. 277 (35): 31567–76. doi:10.1074/jbc.M202723200. PMID 12077128.  
  • Hennig R, Ding XZ, Tong WG, et al. (2002). "5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue.". Am. J. Pathol. 161 (2): 421–8. PMID 12163367.  
  • Ito N, Yokomizo T, Sasaki T, et al. (2003). "Requirement of phosphatidylinositol 3-kinase activation and calcium influx for leukotriene B4-induced enzyme release.". J. Biol. Chem. 277 (47): 44898–904. doi:10.1074/jbc.M208051200. PMID 12244116.  
  • Tong WG, Ding XZ, Hennig R, et al. (2003). "Leukotriene B4 receptor antagonist LY293111 inhibits proliferation and induces apoptosis in human pancreatic cancer cells.". Clin. Cancer Res. 8 (10): 3232–42. PMID 12374694.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Yokomizo T, Noiri E, Izumi T, Shimizu T (2003). "In vivo chemotaxis using CHO cells expressing human leukotriene B4 receptor.". Adv. Exp. Med. Biol. 507: 357–61. PMID 12664610.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message