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Levomethorphan: Wikis


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Systematic (IUPAC) name
CAS number 125-68-8
ATC code R05DA09
PubChem 5486607
DrugBank APRD00655
Chemical data
Formula C 18H25NO 
Mol. mass 271.397 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3-6 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule II
Routes  ?

Levomethorphan is the l-stereoisomer of methorphan. The effects of the two isomers are quite different. Dextromethorphan is an antitussive at low doses and a dissociative at much higher doses, whereas levomethorphan is an opioid analgesic. Levomethorphan has effects similar to levorphanol but is less potent as it must be demethylated to the active form by liver enzymes before becoming active.

See also


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