Edelstein at the Fox House Mercedes-Benz Fashion Week 2007, September 2007
|Born||May 21, 1966
Boston, Massachusetts, U.S.
Edelstein was born to Alvin and Bonnie Edelstein in Boston, Massachusetts. Her family is Jewish, and her father is a pediatrician in New Jersey at Chilton Memorial Hospital. The youngest of three children, she was raised in Wayne, New Jersey and attended Wayne Valley High School, graduating in 1984. She moved to New York City at the age of 18 to study theatre at New York University's Tisch School of the Arts. While living in New York, she became involved in the club scene (known there only as "Lisa E.") and caused enough of a stir in the community to be dubbed New York City's "Queen of Downtown" by writer and fellow celebutante James St. James, who briefly refers to Edelstein in his 1999 book Disco Bloodbath.
After being dubbed a "celebutante" by New York Times magazine during her club kid days, Edelstein used her newfound celebrity to write, compose and star in an original musical called Positive Me in response to the growing AIDS crisis of the 1980s. After a brief stint hosting Awake on the Wild Side for MTV in 1990, she spent the early '90s appearing in guest roles on several popular comedies, including Mad About You, Wings, The Larry Sanders Show, Sports Night and Seinfeld, where she played George Costanza's frustrated girlfriend, the "Risotto Girl".
Bigger roles in TV dramas soon followed, among them the lesbian sister on ABC's Relativity in 1996; Rob Lowe's date turned high-priced call girl on The West Wing in 1999; a male-to-female transsexual on Ally McBeal in 2000 and Ben's girlfriend on Felicity in 2001. She also continued to land guest star spots on shows such as ER, Frasier, Just Shoot Me!, Without a Trace and Judging Amy.
The actress has lent her voice to several animated programs including King of the Hill, American Dad!, Superman: The Animated Series (as Mercy Graves, Lex Luthor's bodyguard, a role she later reprised in several episodes of Justice League) and the 1997 video game adaptation of Blade Runner. Edelstein's film credits include What Women Want with Mel Gibson, Keeping the Faith with Ben Stiller, a cameo in As Good as it Gets with Jack Nicholson & Helen Hunt and Daddy Day Care with Eddie Murphy.
In 2004, she was cast as Dr. Lisa Cuddy, the Dean of Medicine at Princeton-Plainsboro Teaching Hospital and frequent character foil to title character Gregory House (Hugh Laurie) on Fox's hit show House, M.D..
Edelstein currently resides in Los Angeles with her cat and three rescue dogs. She is a vegetarian and an avid practitioner of Mysore style Ashtanga Yoga. She frequently volunteers for the Best Friends Animal Society. In her spare time she enjoys writing, painting and composing music.
|1991||The Doors||Makeup Artist|
|1997||As Good as It Gets||Woman at Table|
|1998||Susan's Plan||Penny Myers|
|2000||Keeping the Faith||Ali Decker|
|What Women Want||Dina|
|2002||Obsessed||Charlotte (imaginary hot doctor)|
|2003||Daddy Day Care||Crispin’s Mother|
|2005||Fathers and Sons||Irene|
|Say Uncle||Sarah Faber|
|2008||Special Delivery||Maxine Carter|
|1992||Mad About You||Lynne Stoddard||1 episode|
|1995–1997||Almost Perfect||Patty Karp||9 episodes|
|1996-1997||Relativity||Rhonda Roth||Episode 1 to Episode 17|
|Superman: The Animated Series||Mercy Graves||8 episodes|
|1997||ER||Aggi Orton||"Ambush (S4E1)"|
|1998||Just Shoot Me!||Erin Simons||"Sewer!"|
|Frasier||Caitlin||"Frasier Gotta Have It"|
|1999||Sports Night||Bobbi Bernstein||3 episodes|
|1999–2000||The West Wing||Laurie "Brittany" Rollins||5 episodes|
|2000–2001||Ally McBeal||Cindy McCauliff||5 episodes|
|2002||Leap of Faith||Patty||Episode 1 to Episode 6|
|2003||Without a Trace||Dr. Liana Sardo||Moving On|
|The Practice||Diane Ward||2 episodes|
|Justice League||Mercy Graves||1 episode|
|2004||Judging Amy||Sylvia Danforth||"The Quick and the Dead"|
|2004–present||House, M.D.||Dr. Lisa Cuddy||Regular cast member|
|2005||Justice League Unlimited||Mercy Graves||1 episode|
|2007||"King Of The Hill"||Powder Puff Boys||Season 12 Episode 3|