This is a list of fictional supervillain characters originating in motion pictures.
| Name | Film |
|---|---|
| The Crimson Ghost | The Crimson Ghost |
| Dr. Evil | Austin Powers: International Man of Mystery |
| The Lightning | The Fighting Devil Dogs |
| Professor Ratigan | The Great Mouse Detective |
| Syndrome | The Incredibles |
| Unicron | The Transformers: The Movie |
| King Ghidorah | Godzilla (franchise) |
| Dr. Horrible | Dr. Horrible's sing-along blog |
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