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List of omics topics in biology: Wikis


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Inspired by the terms genome and genomics, other words to describe complete datasets of biological data, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome).


List of topics

-ome Field of study
Collection of Parent subject Notes
Bibliome Bibliomics Scientific bibliographic data
Cytome Cytomics Cellular systems of an organism Cytology
Exposome (2005) Exposomics An individual's environmental exposures, including in the prenatal environment Molecular genetics A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture").[1]
Exposome (2009) Composite occupational exposures and occupational health problems Occupational safety and health The proposers of this term were aware of the previous term as used above but proposed to apply the term to a new field.[2][3]
Exome Exomics Exons in a genome
Genome Genomics
(Classical genetics)
(DNA sequences/Chromosomes)
Genetics "Genome" refers to the set of all genes in an organism. However, "genome" was coined decades before it was discovered that most DNA is "non-coding" and not part of a gene; thus, "genome" originally referred to the entire collection of DNA within an organism. Today, both definitions are used, depending on the context.[4]
Glycome Glycomics Glycans glycobiology
Interactome Interactomics All interactions The term "interactomics" is generally not used. Instead, interactomes are considered the study of systems biology.[5][6]
Ionome Ionomics Inorganic biomolecules
Kinome Kinomics Kinases Proteins that add a phosphate group
Lipidome Lipidomics Lipids
Mechanome Mechanomics The mechanical systems within an organism
Metabolome Metabolomics Metabolites All products of a biological reaction (including intermediates)
Metagenome Metagenomics Genetic material found in an environmental sample The genetic material is assumed to contain DNA from multiple organisms and therefore multiple genomes, hence the inclusion of the prefix meta-.
Metallome Metallomics Metals and metalloids
ORFeome ORFeomics Open reading frames (ORFs)
Pharmacogenome Pharmacogenomics SNPs and their effect on pharmacokinetics and pharmacodynamics Pharmacogenetics
Phenome Phenomics Phenotypes
Physiome Physiomics Physiology of an organism
Proteome Proteomics Proteins
Regulome Regulomics Transcription factors and other molecules involved in the regulation of gene expression
Speechome Speecheomics Influences on language acquisition Coined by the Human Speechome Project[7]
Transcriptome Transcriptomics mRNA transcripts

Hierarchy of topics

For the sake of clarity, some topics are listed more than once.


  1. ^ Wild CP (2005). "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology". Cancer Epidemiol. Biomarkers Prev. 14 (8): 1847–50. doi:10.1158/1055-9965.EPI-05-0456. PMID 16103423.  
  2. ^ Faisandier, Laurie; De Gaudemaris, Régis; Bicout, Dominique J. (submitted 20 June 2009). Occupational Health Problem Network : the Exposome.   arΧiv:0907.3410
  3. ^ Faisandier, Laurie; Bonneterre, Vincent; De Gaudemaris, Régis; Bicout, Dominique J. (submitted 20 June 2009). A network-based approach for surveillance of occupational health exposures.   arΧiv:0907.3355
  4. ^ "genome, n.". Oxford English Dictionary. March 2008.  
  5. ^ [1]
  6. ^ [2]
  7. ^ BBC article on the Speechome Project

External links



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