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"Little Sister"
Single by Queens of the Stone Age
from the album Lullabies to Paralyze
Released	March 7, 2005
Genre	Hard rock, stoner rock
Length	2:54
Label	Interscope Records
Writer(s)	Joey Castillo Joshua Homme Troy Van Leeuwen
Producer	Joe Barresi Joshua Homme
Queens of the Stone Age singles chronology
"First It Giveth" (2003) "Little Sister" (2005) "In My Head" (2005)

"Little Sister" was the first single released by the rock group Queens of the Stone Age from their fourth album Lullabies to Paralyze. The song was recorded live in the studio in one take.

The song had been in the works for quite a while. An early version was recorded with Dave Grohl in 2002 for the album Songs for the Deaf, but was scrapped. The unfinished recording was later distributed on a bootleg recording compilation. According to Josh Homme, the song was inspired by the "sort of sexual twist" of Doc Pomus's song of the same name, which is probably best known as recorded by Elvis Presley.

When this song was performed on Saturday Night Live on May 14, 2005, actor/comedian Will Ferrell, who hosted the show, came onstage and played the cowbell as fictional Blue Öyster Cult member Gene Frenkle. This was a reprise of a role that Ferrell played in a famous 2000 sketch in which actor Christopher Walken demands, "More cowbell!" during the studio recording of that band's famous song, "(Don't Fear) The Reaper", much to the chagrin of the rest of the band. The cowbell sound is in fact made by a jam block, as seen on the music video for the song. The song has also been featured in the show Entourage.

It has also been featured in the video games Midnight Club 3: DUB Edition, Colin McRae: Dirt 2, and Project Gotham Racing 3. Additionally, it appears in the music video game series Rock Band as downloadable content individually or in a 3-song pack along with two other Queens of the Stone Age songs, "3's and 7's" and "Sick, Sick, Sick".

Music video

The music video features the band members playing in a dark room, with singer Josh Homme sporting a longer hair style, and girls dancing in the back behind a silhouette screen. The video shows the cowbell noise as being performed with a Jamblock.

Track listings

CD:

1. "Little Sister" (Album Version) - 2:57
2. "The Blood Is Love" (Contradictator Remix) - 5:24
3. "Little Sister" (CD-ROM video)

CD Maxi Single:

1. "Little Sister" (Album Version) - 2:57
2. "The Blood Is Love" (Contradictator Remix) - 5:24
3. "Little Sister" (Contradictator Remix) - 3:29

7" (Picture Disc):

1. "Little Sister" (Album Version) - 2:57
2. "Little Sister" (Contradictator Remix) - 3:29