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Updated live from Wikipedia, last check: June 02, 2012 15:31 UTC (40 seconds ago)

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Lomerizine
Systematic (IUPAC) name
1-[bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazine
Identifiers
CAS number 101477-55-8
ATC code none
PubChem 3949
Chemical data
Formula C 27H30F2N2O3  
Mol. mass 468.53 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status ℞ Prescription only
Routes Oral

Lomerizine (INN) is a calcium channel blocker[1] with antimigraine properties.

References

  1. ^ Selt M, Bartlett CA, Harvey AR, Dunlop SA, Fitzgerald M (November 2009). "Limited restoration of visual function after partial optic nerve injury; a time course study using the calcium channel blocker lomerizine". Brain Res. Bull.. doi:10.1016/j.brainresbull.2009.11.004. PMID 19913075. http://linkinghub.elsevier.com/retrieve/pii/S0361-9230(09)00354-2.  
Antimigraine preparations (N02C)
Analgesic/abortive
Serotonin modulators
Ergot alkaloids
Other
Other
Prevention of migraines
Ungrouped
#WHO-EM. ‡Withdrawn from market. CLINICAL TRIALS: †Phase III. §Never to phase III







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